APE-Gen: A Fast Method for Generating Ensembles of Bound Peptide-MHC Conformations
The Class I Major Histocompatibility Complex (MHC) is a central protein in immunology as Kits it binds to intracellular peptides and displays them at the cell surface for recognition by T-cells.The structural analysis of bound peptide-MHC complexes (pMHCs) holds the promise of interpretable and general binding prediction (i.e., testing whether a gi